Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
genetic toxicity in vivo
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
other: Not applicable since exclusively summarizing data coming from an existing risk assessment (BUA Report) are presented as executive summary.

Data source

Reference
Reference Type:
other: Risk assessment
Title:
Phenylenediamines, BUA Report 97
Author:
GDCh-Advisory Committee on Existing Chemicals of Environmental Relevance (BUA)
Year:
1992
Bibliographic source:
edited by the GDCh-Advisory Committee on Existing Chemicals of Environmental Relevance, S. Hirzel, Wissenschaftliche Verlagsgesellschaft, Birkenwaldstraße 44, 70191 Stuttgart, 1995

Materials and methods

Results and discussion

Applicant's summary and conclusion

Executive summary:

The results of in vivo studies of gene mutation and DNA and chromosomal damage were frequently negative with p-phenylenediamine.