(1S,4R,4aS,9aR)-4,4a,9,9a-tetrahydro-1H-1,4-methanofluorene

Biodegradation in water: screening tests

Link to relevant study record(s)

Reference

Endpoint:

biodegradation in water: ready biodegradability

Type of information:

experimental study

Adequacy of study:

key study

Study period:

14 August 1996 - 22 October 1996

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: The study was conducted in compliance with the Good Laboratory Practise

Qualifier:

according to guideline

Guideline:

other: Test Method Relating to New Chemical Substances (Kanpogyou No.5, Yakuhatsu No.615, 49 Kikyoku No.392, 1974)

GLP compliance:

yes

Oxygen conditions:

anaerobic

Inoculum or test system:

activated sludge (adaptation not specified)

Duration of test (contact time):

28 d

Key result

Parameter:

% degradation (DOC removal)

Remarks on result:

not determinable because of methodological limitations

Remarks:

Degradability was not calculated because the test substance was insoluble in water.

Details on results:

During the course of the study, 17-43% of the test substance in bottles 3-5 and 54% of the test substance in bottle 6 disappeared. This could be due to volatilization of the dissolved test substance.

In additional test it was confirmed that the disappearance of the test substance was due to volatilization.

Degradability was not calculated because the test substance was insoluble in water.

Because the test substance concentration in the bottle 6 was less than 90% of the theoretical value, disappearance rate was shown instead of degradability.

Disappearance rate in bottles 3 -6:

3: 33%

4: 43%

5: 17%

6: 54%

Interpretation of results:

under test conditions no biodegradation observed

Description of key information

MTF is considered not to be readily biodegradable.  

Key value for chemical safety assessment

Biodegradation in water:

inherently biodegradable

Additional information

A biodegradation study (Yokohama Laboratory, Mitsubishi Chemical Safety Institute Ltd. (M.S.I.), 1996) was conducted to assess the ready biodegradability of MTF in water. The study was conducted according to official test methods (Test Method Relating to New Chemical Substances, Kanpogyo No. 5, Yakuhatsu No. 615, 49 Kikyoku No. 392, 1974) and in compliance with GLP.

On the basis of oxygen consumption, the test material was found not to have degraded over the 28 -day monitoring period.

On this basis, MTF is considered not to be readily biodegradable. It was noted that residual test material concentrations in media had decreased over the monitoring period, however this was considered to have been due to volatilization.