Registration Dossier
Registration Dossier
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EC number: 252-046-8 | CAS number: 34455-29-3
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Remarks:
- The study was conducted according to the test guidelines in effect at the time of study conduct
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Remarks:
- The study was conducted according to the test guidelines in effect at the time of study conduct
- GLP compliance:
- yes
- Type of method:
- other: turbidimetry
- Key result
- Water solubility:
- ca. 50 mg/L
- Temp.:
- 20 °C
- pH:
- >= 4.4 - <= 7.7
- Conclusions:
- This study and the conclusions which are drawn from it fulfil the quality criteria (validity, reliability, repeatability).
The water solubility was estimated to be approximately 50 mg/L. - Executive summary:
Water solubility was determined in accordance with OECD Guideline 105. An accurately weighed portion of the test item was dispersed in purified water by stirring for 1 day at 20˚C. Serial dilutions (1:1 v/v) of this sample were then performed with purified water. The turbidity of each dilution was measured in triplicate and the pH recorded. Logarithmic graphs of the mean turbidity versus concentration were plotted and a linear regression performed on each half of the curve. The intercept point of the regression lines was taken as the estimated water solubility value. This process was conducted in duplicate.
The water solubility was estimated to be approximately 50 mg/L (slightly soluble).
Reference
Description of key information
ca. 50 mg/L at 20°C and pH 4.4-7.7
Key value for chemical safety assessment
- Water solubility:
- 50 mg/L
- at the temperature of:
- 20 °C
Additional information
OECD Guideline 105
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