Registration Dossier
Registration Dossier
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EC number: 473-820-3 | CAS number: -
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics
- Type of information:
- other: Literature based toxicokinetic assessment
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only short abstract available
Data source
Materials and methods
- Objective of study:
- other: Assessment of toxicokinetic behaviour
Test guideline
- Qualifier:
- no guideline available
- GLP compliance:
- no
Test material
Constituent 1
- Radiolabelling:
- no
Results and discussion
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): other: unlikely to be available for metabolism or excretion
The substance is unlikely to be absorbed orally or dermally, and is unlikely to be inhaled and retained. - Executive summary:
Given the solubility profile and particle size, the substance is unlikely to be absorbed orally or dermally, and is unlikely to be inhaled and retained. Given the solubility of the material, it is also unlikely to become available for metabolism or excretion. If particles lodge in the alveolus following inhalation, they will be dealt with largely as insoluble particulates, and if the substance is administered orally it is likely to appear in faeces unabsorbed.
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