calcium (1R,2S)-cyclohexane-1,2-dicarboxylate

Biodegradation in water: screening tests

Description of key information

The test material is readily biodegradable.

Key value for chemical safety assessment

Biodegradation in water:

readily biodegradable

Additional information

Two studies are available to address this endpoint. Both were conducted in accordance with standardised guidelines under GLP conditions. Both were awarded a reliability score of 1 in accordance with the criteria for assessing data quality set forth by Klimisch et al. (1997).The key study has been selected on the basis that the OECD 301 B study is historically more sensitive than the OECD 301 C study.

 

In the key study, the biodegradation of the test material was investigated in accordance with the standardised guidelines OECD 301 B and EU Method C.4-C under GLP conditions.

Activated sludge (domestic, non-adapted) was exposed to the test material under aerobic conditions for 28 days at an initial concentration of 21.9 mg/L. CO₂ evolution was followed to determine the extent of biodegradation.

The test material attained 74 % degradation after 28 days and satisfied the 10-Day window validation criterion. The test material can therefore be considered to be readily biodegradable.

 

In the supporting study, the biodegradation of the test material was investigated in accordance with the standardised guideline OECD 301 C under GLP conditions.

Activated sludge (adaptation not specified) was exposed to the test material under aerobic conditions for 28 days at an initial concentration of 100 mg/L. BOD and DOC removal were followed to determine the extent of biodegradation.

Some of the anionic component of the test material (1,2-cyclohexanedicarboxylic acid ion) was biodegraded by microorganisms and changed into a structure-unknown converted product. The structure-unknown converted product and the rest of the anionic component of the test material were not biodegraded by microorganisms and remained.