1,2,4,5,7,8-Hexoxonane, 3,6,9-trimethyl-, 3,6,9-tris(Ethyl and Propyl) derivatives (upper limit: 41% w/w; typical concentration: 38% w/w)

Bioaccumulation: aquatic / sediment

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

bioaccumulation in aquatic species: fish

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

other:

Reference 2

Endpoint:

bioaccumulation in aquatic species: fish

Type of information:

(Q)SAR

Adequacy of study:

supporting study

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

results derived from a (Q)SAR model, with limited documentation / justification

Conclusions:

BCF derived with measured water solubility limit (13.1 mg/L) and measured log Kow value (4.84) is 725 L/kg (Log BCF = 2.86).
With an estimated log Kow value (by EPISuite) of 6.1 the BCF estimate is 4940 L/kg (Log BCF = 3.69).

Description of key information

This study is waived because for the PBT/vPvB assessment the P will be addressed first. A simulation study is proposed.  Furthermore, the main component has an estimated BCF of 725 L/kg, which is below the threshold for B-classification.

1,2,4,5,7,8-Hexoxonane, 3,6,9-trimethyl-, 3,6,9-tris(Ethyl and Propyl) derivatives is only used in industrial settings (manufacture, and downstream use) with no wide dispersive uses.  This test is waived as releases to the aquatic compartment are very unlikely due to the highly contained processes during manufacture and downstream (industrial) use.