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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Link to relevant study record(s)

Reference
Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Qualifier:
according to
Guideline:
other: Toxicity experiments were conducted following U.S. Environmental Protection Agency guidance 1994. Methods for measuring the toxicity of sediment-associated contaminants with estuarine and marine amphipods. EPA 600/R-94/025. Narragansett, RI
GLP compliance:
not specified
Test organisms (species):
other: amphipod: Eohaustorius estuarius
Water media type:
saltwater
Total exposure duration:
10 d
Duration:
10 d
Dose descriptor:
LC50
Effect conc.:
36 other: mg/kg dw
Remarks on result:
other: 95% CI; YB sediment
Duration:
10 d
Dose descriptor:
LC50
Effect conc.:
23 other: mg/kg dw
Remarks on result:
other: 95% CI, SDB sediment
Duration:
10 d
Dose descriptor:
NOEC
Effect conc.:
24 other: mg/kg dw
Remarks on result:
other: 95% CI, YB sediment
Duration:
10 d
Dose descriptor:
NOEC
Effect conc.:
20 other: mg/kg dw
Remarks on result:
other: 95% CI; SDB sediment
Duration:
10 d
Dose descriptor:
LOEC
Effect conc.:
44 other: mg/kg dw
Remarks on result:
other: 95% CI; YB sediment
Duration:
10 d
Dose descriptor:
LOEC
Effect conc.:
38 other: mg/kg dw
Remarks on result:
other: 95% CI; SDB sediment
Executive summary:

Lowest NOEC value is 20 mg/kg, whereas density is 1.64 kg/m3 (0.00164 kg/L)

NOEC 20 mg/kg = 0.0328 mg/L

Description of key information

NOEC for marine water invertabrates has been recalculated from NOEC mg/kg based on substance density (publication nr 25).

Lowest NOEC value is 20 mg/kg, whereas density is 1.64 kg/m3 (0.00164 kg/L)

NOEC 20 mg/kg = 0.0328 mg/L

Key value for chemical safety assessment

EC10, LC10 or NOEC for marine water invertebrates:
0.033 mg/L

Additional information