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Ecotoxicological information

Long-term toxicity to fish

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Reference
Endpoint:
long-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods
Qualifier:
equivalent or similar to guideline
Guideline:
other: Modified U.S. Environmental Protection Agency. 2002. Methods for measuring the acute toxicity of effluents and receiving waters to freshwater and marine organisms, 5th ed. EPA-821-R-02-012. Office of Water, Washington, DC
GLP compliance:
not specified
Test organisms (species):
Pimephales promelas
Test type:
semi-static
Water media type:
freshwater
Total exposure duration:
10 d
Duration:
10 d
Dose descriptor:
LC50
Effect conc.:
2.2 mg/L
Nominal / measured:
meas. (geom. mean)
Conc. based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: 95% CL

LC50 (10 d): > 9.17 — < 10.22 µmol/L test mat. (meas. (geom. mean)) based on: mortality (95% CL)

Description of key information

Median lethal concentration of 9.68 µmol/L (2.20 mg/L; 95% CL, 9.17 -10.22 µmol/L) was calculated in 10 -d experiments.

LC50: 2.20 mg/L

Key value for chemical safety assessment

Additional information