Registration Dossier
Registration Dossier
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EC number: 209-406-4 | CAS number: 577-11-7
Endpoint summary
Administrative data
Description of key information
BCF (42-day, carp, steady state, 4.1% lipid content): 9.33 L/kg
Additional information
An experimental study (Arnot & Gobas 2006, 42 day exposure, steady state) resulted in a BCF of 9.33 L/kg in carp (4.1% lipid content). A further 72 -hour study (Goodrich et al. 1991) with rainbow trout resulted in a BCF of 3.78 L/kg in carcas. In addition to the experimental results, a QSAR using the BCFBAF (v3.01) module implemented in EPISuite 4.11 resulted in a BCF of 52.6 L/kg. Hence there was a good agreement between the experimental values and the QSAR.
For the risk assessment, a BCF of 9.33 L/kg will be used since this study is considered to be scientifically most relevant study. The use of the more conservative QSAR result would not have had a different outcome for e.g. the PBT assessment.
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