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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Additional toxicological data

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Administrative data

Endpoint:
additional toxicological information
Adequacy of study:
disregarded due to major methodological deficiencies

Data source

Reference
Reference Type:
publication
Title:
An evaluation of the utility of four in vitro short term tests for predicting the cytotoxicity of individual compounds derived from tobacco smoke.
Author:
Curvall M., Enzell C.R. and Pettersson B.
Year:
1984
Bibliographic source:
Journal Cell Biology and Toxicology, Vol. 1, p.173-193.

Materials and methods

Type of study / information:
Type: other: cytotoxicity: evaluation of the short-term tests for predicting the cytotoxicity

Test material

Constituent 1
Chemical structure
Reference substance name:
Mequinol
EC Number:
205-769-8
EC Name:
Mequinol
Cas Number:
150-76-5
Molecular formula:
C7H8O2
IUPAC Name:
4-methoxyphenol
Details on test material:
The origin of p-methoxyphenol was not reported.

Results and discussion

Any other information on results incl. tables

Based on its toxicity in all four systems (A(cg)=9, A(om)=1, A(ca)=0 and  A(md)=0) 
p-methoxyphenol showed a low mean activity, A(t) = 2.5.

Applicant's summary and conclusion