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EC number: 252-558-1
CAS number: 35435-21-3
[triethoxy(2,4,4-trimethylpentyl)silane]: Not relevant
[(2,4,4-trimethylpentyl)silanetriol]: pKa approximately 10
The requirement to test the
substance for dissociation constant is waived because there are no
ionisable groups present in the molecule. However, in contact with water
the substance hydrolyses moderately to form
(2,4,4-trimethylpentyl)silanetriol and ethanol.
There are no reliable measured
data for the dissociation constant of
(2,4,4-trimethylpentyl)silanetriol. The typical dissociation constants
for the hydroxyl protons of silanetriols are available from studies in
other silanetriols. It is appropriate to read-across dissociation
constant data for (2,4,4-trimethylpentyl)silanetriol from
phenylsilanetriol. This suggests that silanols are not expected to
undergo significant dissociation within the range of pH relevant in the
environment or in vivo.
Phenylsilanetriol has a measured
first dissociation constant approximately 10 in a reliable study using a
relevant test method. Additional information is given in a supporting
report (PFA, 2013b) attached in Section 13.
PFA (2013b). Peter Fisk
Associates, Dissociation constant Analogue report, PFA.300.001.001
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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