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Environmental fate & pathways

Adsorption / desorption

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In accordance with Section 2 of Annex XI of Regulation (EC) No. 1907/2006 (REACH), it is considered justified to omit the study required under point 9.3.1 of Annex VIII on the basis that testing is not technically possible. 
The substance is known to be poorly soluble in water and appropriate organic solvents. Furthermore, the analytical methods for this substance have limited sensitivity and would not produce a meaningful result. This is demonstrated by the difficulties experienced in the study submitted as supporting information for the data requirement 9.2.2.1 Hydrolysis as a function of pH, where attempts to determine the behaviour of the read across substance DOTO (n-dioctyltin oxide) under hydrolysis using electrospray ionisation mass spectrometry (ESI/MS) did not produce any results due to the difficult nature of the substance. Furthermore, calculation of the adsorption coefficient is not appropriate for organotin substances, as there is currently no QSAR or QSPR validated for such an estimation.

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