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EC number: 940-592-6 | CAS number: -
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
Determination of the Abiotic Degradation. (Hydrolysis as Function of pH) [OECD 111]
Key value for chemical safety assessment
Additional information
The test material was dissolved in aqueous solutions buffered at pH 4, 7 and 9 and incubated at 50 ± 1.2°C for maximum of 5 days.
In the incubated samples at pH 4 and 7 a significant decline of the test item concentration was observed. After 5 days of incubation more than 90% of the initial concentrations could be observed.
A main test was to be perfomed at pH 4 and pH 7.
In case of samples incubated at pH 9 the test item degraded rapidly to 24.14% directly after application. After 2.4 hours 6.01% of the initial concentration was found in the samples.
As the test item was very unstable at alkaline conditions (confirmed by the accuracy values of 22% and 36%) Hydrolysis at pH 9 was not feasible. No main test was performed at pH 9.
Samples at pH 4 were incubated at 20°C, 30°C and 50°C for 17 d, 6d and 48 hours.In the incubated samples a significant decline of the test item concentration was observed. At the end of incubation <10% of the initial concentration could be found. Under environmental relevant conditions (20°C) <10% of the initial amount were detected after 17 days of incubation.
Samples at pH 7 were incubated at 20°C, 30°C and 50°C for 14 d, 7d and 48 hours.In the incubated samples a significant decline of the test item concentration was observed. At the end of incubation <10% of the initial concentration could be found. Under environmental relevant conditions (20°C) <10% of the initial amount were detected after 14 days of incubation.
For reaction at pH 4 and pH 7 the Arrhenius
relationship was calculated based on data generated at 20, 30 and 50 °C.
Logarithm of the rate constants were plotted against the reciprocal of
the absolute temperature.
Following relation was found:
pH 4: ln k = - 8102 * 1/T + 23
pH 7: ln k = - 9356 * 1/T + 27
At pH 4 and pH 7, the test item is degraded by hydrolysis. The half-life of reaction at 20°C was determined to be 106 hours at pH 4 and 82 hours at pH 7.At pH 9 the test item supposed to be hydrolytically unstable and degraded immediately.
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