Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 618-882-6
CAS number: 928771-01-1
potential was assessed in a GLP-compliant guideline study (method B10 of
directive 2004/73/EC). Based on results obtained from an initial
cytotoxicity screen, test concentrations of 312.5-2500 ug/ml were used
in the absence and in the presence of phenobarbitone/B-naphthaflavone
induced rat S9 fraction, and the study run using 2 independent repeats.
An oily precipitate was observed at 1250 ug/plate and above, but this
was not cytotoxic. No increase in the frequency of cells with
aberrations or the incidence of polyploidy was recorded in two
independent experiments in the absence or presence of S9 fraction, up to
the maximum dose tested (2500 ug/ml). A satisfactory response was
obtained with the positive control substances (-S9 mitomycin c; +S9
cyclophosphamide) in both experiments. The results indicate that NExBTL renewable
diesel is not clastogenic to human lymphocytes in vitro.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again