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EC number: 618-882-6
CAS number: 928771-01-1
Results are available from two modern, GLP-compliant, guideline studies that have assessed the skin and eye irritation potential of NExBTL renewable diesel in the rabbit. Knowledge of the chemistry of the substance and its low vapour pressure indicates it will not be irritating to the respiratory tract.
The skin and eye irritation potential of
undiluted NExBTL renewable diesel was
determined in two guideline tests conducted using the rabbit (method B4
and method B5 of directive 2004/73/EC, respectively). Both studies were
GLP-compliant and the information is reliable and fully adequate for
evaluation. The test substance caused mild, fully reversible irritation
in both studies, however the magnitude and duration of the responses
obtained were insufficient to require classification. Observations made
during a guideline acute dermal toxicity study (method B3 of directive
2004/73/EC) suggest that NExBTL renewable diesel may cause
solvent-related defatting of the skin.
No classification required under Directive
67/548/EEC or Regulation EC 1272/2008 for skin or eye irritation
(severity and duration scores below threshold for classification).
However solvent-related defatting of skin indicates that R66 and the
supplemental hazard statement EUH066 (Repeated exposure may cause skin
dryness or cracking) should be applied according to Directive 67/548/EEC
Regulation EC 1272/2008 or Regulation EC 1272/2008, respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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