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Long-term toxicity to fish

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Description of key information

The chemical safety assessment according to Annex I does not indicate the need to investigate further the effects (long-term toxicity or bioconcentration) on aquatic organisms. 

Key value for chemical safety assessment

Additional information

Due to high lipophilicity of the substance (with the average log Kow 8.4), 98.2 % of it will end up in sediment if it is continuously released in water at a constant rate (estimated using EQC Equilibrium Criterion Model 2.02). After a single spill, more than 99.9 % of the substance will be found in sediment at the equilibrium (calculated based on Koc = 3.78x103from Sabljic et al 1995). Furthermore, the substance was found readily biodegradable in a test carried out according OECD Guideline 301B (Ready biodegradability; CO2Evolution Test). Therefore, water phase may serve as a significant exposure route only in acute exposures and in chronic exposures, the concentrations of the substance in water phase will be very low. Thus, a chronic toxicity test or bioconcentration test with fish are not relevant. Since numerous studies have shown that elimination of alkanes by aquatic species (e.g. Neff et al 1976 and Middleditch and Basile 1980) is fast, bioaccumulation of the test material by fish via food chain is not likely.


Middleditch BS,Basile B(1980) Alkanes in benthic organisms from the Buccaneer oil field,Bulletin of Environmental Contamination and Toxicolology 24(6), 945-52.  

Neff JM, Cox BA, Dixit D and Anderson JW (1976) Accumulation and release of petroleum-derived aromatichydrocarbons by four species of marine animals, Marine Biology 38, 279-289.

Sabljic A, Güsten H, Verhaar H and Hermens J (1995) QSAR modeling of soil sorption - improvements and systematics of Log Koc vs Log Kow correlations, Chemosphere 31, 4489 -4514