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EC number: 269-052-1 | CAS number: 68186-90-3 This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 77310.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- no hazard identified
Marine water
- Hazard assessment conclusion:
- no hazard identified
STP
- Hazard assessment conclusion:
- no hazard identified
Sediment (freshwater)
- Hazard assessment conclusion:
- no hazard identified
Sediment (marine water)
- Hazard assessment conclusion:
- no hazard identified
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- insufficient hazard data available (further information necessary)
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
As defined in Part B, Section 1 of the Chemical Safety Report, the substance is an inorganic compound with very low solubility. Therefore, there are no mandatory testing requirements for any of the required ecotoxicological endpoints. As a result, the determination of PNEC levels for this substance that are based on ecotoxicological studies cannot be conducted.
A transformation/dissolution test according to OECD 29 with the substance, however, demonstrated that small amounts of the individual inorganic building blocks of this substance (i.e., the elements Chromium and Antimony) could be released in aqueous media. It was shown in a screening test that the highest release of Cr and Sb occurred at pH 8.5. Therefore, it was decided to conduct the full test at the most relevant pH with respect to ecotoxicology, i.e. at pH 8.5. Furthermore, Sb is of no eco-toxicological relevance compared to Cr given by the available aquatic endpoints derived from test with aquatic organisms: The acute and chronic ERV for Antimony is 1770 and > 1000 µg Sb/L (European Union Risk Assessment Report, 2008, see: https://echa.europa.eu/documents/10162/13630/trd_rar_sweden_diantimony_trioxide_en.rtf). For CrIII the acute ERV is 320 µg/L and the chronic ERV is 47 µg /L for acidic and alkaline pH values. The acute and chronic (ERVs) which are comparable to the most sensitive aquatic ecotoxicological endpoint were taken from the report "Proposed Environmental Quality Standards for Water Framework Directive" see https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/291229/scho0407blvq-e-e.pdf.
The third inorganic builing block titanium was not taken into acoount here since it is not of any ecotoxicological relevance.
Conclusion on classification
The transformation and dissolution of CrIII and Sb from the substance was evaluated according to the T/D Protocol (OECD 29) (transformation/dissolution protocol, see section 4.8 attached).
The full test was performed at 1, 10 and 100 mg/L loadings for 7 days and at 1 mg/L loading for 28 days and at the pH of maximum release of the most metals, i.e. at pH 8.5.
The acute and chronic Ecotoxicity Reference Values (ERVs) for Cr were taken from a document prepared by EA UK, 2008: Proposed Environmental Quality Standards for Water Framework Directive:
The acute ERV is 320 µg Cr/L and the chronic ERV is 47 µg Cr/L for acidic and alkaline pH values. The mean Cr concentration of three replicates/concentrations was 0.07, 0.13 and 0.28 µg Cr/L at a loading rate of 1, 10 and 100 mg/L and after 7 days.
The acute and chronic ERV of Antimony is 1770 and > 1000 µg Sb/L and were taken from the European Union Risk Assessment Report. The mean Sb concentration of three replicates/concentrations was 0.77, 2.26 and 7.7 µg Sb/L at a loading rate of 1, 10 and 100 mg/L and after 7 days.
Consequently, the concentrations of Cr and Sb are far below the acute ERVs of 320 µg/L for Cr and 1770 µg/L for Sb and thus, the compound has not to be acutely classified according to GHS. This is in line with the available aquatic ecotoxicological studies: In short-term toxicity studies, performed with the test substance, no effect were observed up to the limit dose and the following L(E)C50 values were determined (nominal concentrations): LC50 (fish) > 10000.0 mg/L, EC50 (daphnia) > 100.0 mg/L and EC50 (algae) > 100.0 mg/L.
Based on these results, the test substance is not considered to be classified for acute aquatic toxicity.
According to theT/D Protocol (OECD 29), the solubility equilibrium has been established for Cr at the loadings of 1 mg/L, 10 mg/L and 100 mg/L because the concentrations of the last three sampling points do not differ by more than 15%. These requirements are also fulfilled for Antimony for 1 mg/L loading. After 28 days, the mean measured concentrations were 0.06 and 1.0 µg/L for Cr and Sb, respectively. These concentrations are far below the chronic ERVs (47 µg Cr/L and > 1000 µg Sb/L) and thus no chronic classification has to be applied to the substance according to GHS.
In conclusion, the results according to the T/D Protocol compared with the ERVs for the most ecotoxicological relevant metals of the substance shows that the substance has not to be classified according to GHS
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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