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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Reference
Endpoint:
bioaccumulation: aquatic / sediment
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Accepted calculation method
Qualifier:
no guideline required
Principles of method if other than guideline:
Quantative Structure Activity Modeling Program, EpiSuite version 3.20; BCFWin version 2.17
GLP compliance:
no
Key result
Type:
BCF
Value:
>= 160 - <= 263 dimensionless
Remarks on result:
other: The substance is not expected to bioaccumulate in the food chain because it does not exceed the US EPA BCF criteria.

Bioaccumulation Estimates from Log Kow (BCFWIN v2.17): Log BCF from regression-based method = 2.420 (BCF = 263) log Kow used: 6.00 (user entered)

Bioaccumulation Estimates from Log Kow (BCFWIN v2.17): Log BCF from regression-based method = 2.203 (BCF = 159.6) log Kow used: 3.77 (user entered)

Validity criteria fulfilled:
not applicable
Conclusions:
The substance is not expected to bioaccumulate in the food chain because it does not exceed the US EPA BCF criteria.
Executive summary:

The structure of the substance was modeled for Bioaccumulation potential using BCFWIN version 2.17 of the US EPA EPISuite verion 3.20.

Using two experimentally derived octanol/water partition coefficient, the BCF was calculated to be 160 -263 (log 2.2 - 2.4).

The substance is not expected to bioaccumulate in the food chain because it does not exceed the US EPA BCF criteria.

Description of key information

estimated value

Key value for chemical safety assessment

BCF (aquatic species):
263 dimensionless

Additional information