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Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
test procedure similar to OECD 105
Cross-reference
Reason / purpose for cross-reference:
reference to same study
Reference
Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Remarks:
Test procedure according to method of Analytical Expert Group ETAD (Ecological and Toxicological Association of Dyes and Organic Pigment Manufacturer)
Reason / purpose for cross-reference:
reference to same study
Qualifier:
according to guideline
Guideline:
other: Analytical Expert Group ETAD
Principles of method if other than guideline:
Test procedure according to method of Analytical Expert Group ETAD (Ecological and Toxicological Association of Dyes and Organic Pigment Manufacturer)
GLP compliance:
no
Medium:
n-octanol
Solubility:
0.84 mg/L
Temp.:
24 °C
Remarks on result:
other: mean of three measurements

individual results: 0.82 mg/L - 0.85 mg/L - 0.84 mg/L

mean: 0.84 mg/L

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2006

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
yes
Remarks:
modified taking into account the very low solubility of the test substance
Principles of method if other than guideline:
The method for the determination and analytical investigation is according to the method that was agreed upon at the "Analytical Experts Meeting" of ETAD (Basel) on January 12, 2005.
GLP compliance:
no
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
5,12-dihydro-2,9-dimethylquino[2,3-b]acridine-7,14-dione
EC Number:
213-561-3
EC Name:
5,12-dihydro-2,9-dimethylquino[2,3-b]acridine-7,14-dione
Cas Number:
980-26-7
Molecular formula:
C22H16N2O2
IUPAC Name:
2,9-dimethyl-5,12-dihydroquino[2,3-b]acridine-7,14-dione
Test material form:
solid: nanoform

Results and discussion

Water solubility
Water solubility:
5.6 µg/L
Temp.:
24 °C
pH:
ca. 7
Remarks on result:
other: mean of 3 measurements

Any other information on results incl. tables

individual results: 3.0 µg/L - 5.1 µg/L - 8.7 µg/L

mean: 5.6 µg/L

Applicant's summary and conclusion

Conclusions:
the test substance is practically insoluble in water (< 0.1 mg/L)