Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-781-0 | CAS number: 126-30-7
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study meets scientific standards with acceptable restrictions (partly limited documentation, e.g. no details about test substance, post exposure observation period).
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 958
- Report date:
- 1958
Materials and methods
- GLP compliance:
- no
- Limit test:
- no
Test material
- Reference substance name:
- Reference substance 001
- Details on test material:
- no details
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- female
- Details on test animals or test system and environmental conditions:
- no details
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- water
- Doses:
- 1, 2, 3.2, 4, 6.3, 10 g/kg bw
- No. of animals per sex per dose:
- up to 5 rats
- Details on study design:
- no further details
- Statistics:
- no data
Results and discussion
Effect levels
- Sex:
- female
- Dose descriptor:
- LD50
- Effect level:
- 2 800 mg/kg bw
- Mortality:
- 0/1, 0/5, 4/5, 5/5, 1/1, 1/1, 1/1 at 1, 2, 3.2, 4, 6.3, 8, 10 g/kg bw, respectively
- Clinical signs:
- slight to deep narcosis within short time
Any other information on results incl. tables
No further details
Applicant's summary and conclusion
- Conclusions:
- LD50 in rats after i.p. injection was ca. 2800 mg/kg bw.
- Executive summary:
Study meets scientific standards with acceptable restrictions (partly limited documentation, e.g. no details about test substance, post exposure observation period).
The acute toxicity in female rats after i.p. injection was studied. Slight to deep narkosis within short time after application was observed. LD50 in rats after i.p. injection was ca. 2800 mg/kg bw.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
