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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
1999
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Only data from review article available

Data source

Reference
Reference Type:
review article or handbook
Title:
Lithium Hydroxide
Author:
Kushneva, V.S., and R.B. Gorshkova
Year:
1999
Bibliographic source:
Spravochnik po Toksikologii i Gigienicheskim Normativam (PDK) Potentsial'no Opasnykh Khimicheskikh Veshchestv", page 153 (1999)

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Only data from review article available. No guideline or method indicated.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Lithium hydroxide
EC Number:
215-183-4
EC Name:
Lithium hydroxide
Cas Number:
1310-65-2
Molecular formula:
HLiO
IUPAC Name:
lithium hydroxide

Test animals

Species:
mouse

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
363 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
Category 4 based on GHS criteria
Conclusions:
According to the handbook-data, the LD50 of lithium hydroxide is 336.0 +/- 7.8 mg/kg bw after oral administration to mice.
Executive summary:

According to the handbook-data, the LD50 of lithium hydroxide is 336.0 +/- 7.8 mg/kg bw after oral administration to mice.