Registration Dossier
Registration Dossier
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EC number: 211-708-6 | CAS number: 688-84-6
Endpoint summary
Administrative data
Description of key information
Additional information
There are valid test data on 2-EHMA available for short –term toxicity to fish, short-term and long-term toxicity to aquatic invertebrates as well as algae toxicity data.
Concerning long-term toxicity data to fish the situation is as follows:
For 2-EHMA the two most sensitive trophic levels – fish and invertebrates – indicate almost identical ecotoxicity. From the bioaccumulation study there is an additional piece of information – fish metabolise 2-EHMA very fast so that it disappears rapidly from the test vessel and also the depuration after the end of exposure takes place within a few hours. This is directly comparable to what is observed in mammalian systems which share many common pathways and processes. Hence, bioaccumulation and a significantly lower chronic NOAEC is not expected. In conclusion, the current PNEC is likely to provide a more conservative margin of safety and further testing is unlikely to provide a higher level of protection. For the sake of animal welfare, further testing in vertebrates is not necessary and not justified.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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