Registration Dossier

Administrative data

Workers - Hazard via inhalation route

Systemic effects

Long term exposure
Hazard assessment conclusion:
no hazard identified
Acute/short term exposure
Hazard assessment conclusion:
no hazard identified
DNEL related information

Local effects

Long term exposure
Hazard assessment conclusion:
medium hazard (no threshold derived)
Most sensitive endpoint:
skin irritation/corrosion
Acute/short term exposure
Hazard assessment conclusion:
medium hazard (no threshold derived)
Most sensitive endpoint:
skin irritation/corrosion
DNEL related information

Workers - Hazard via dermal route

Systemic effects

Long term exposure
Hazard assessment conclusion:
no hazard identified
Acute/short term exposure
Hazard assessment conclusion:
no hazard identified
DNEL related information

Local effects

Long term exposure
Hazard assessment conclusion:
medium hazard (no threshold derived)
Most sensitive endpoint:
skin irritation/corrosion
Acute/short term exposure
Hazard assessment conclusion:
medium hazard (no threshold derived)
Most sensitive endpoint:
skin irritation/corrosion

Workers - Hazard for the eyes

Local effects

Hazard assessment conclusion:
medium hazard (no threshold derived)

Additional information - workers

Regarding acute and long-term local effects, local irritation on skin and/or mucous membranes, e. g. eye and respiratory tract as primary effect can be expected for fatty acids with a chain length ≤C12 due to the corrosive/irritation properties of the short- and mid-chain fatty acids C6 – C12, respectively.

Since no adequate dose descriptor for the corrosion/irritation effects are observed, no DNEL is calculated for local effects. However, appropriate risk management measures will be identified.

According to table E.3-1 in the “Guidance on information requirements and chemical safety assessment Part E: Risk Characterisation (ECHA, 2016), fatty acids, C8-18 (CAS# 90990-08-2) is allocated to the moderate hazard category based on classification as Skin Corr. 1C (H314) according to Regulation (EC) No 1272/2008.

General Population - Hazard via inhalation route

Systemic effects

Long term exposure
Hazard assessment conclusion:
no hazard identified
Acute/short term exposure
Hazard assessment conclusion:
no hazard identified
DNEL related information

Local effects

Long term exposure
Hazard assessment conclusion:
medium hazard (no threshold derived)
Most sensitive endpoint:
skin irritation/corrosion
Acute/short term exposure
Hazard assessment conclusion:
medium hazard (no threshold derived)
Most sensitive endpoint:
skin irritation/corrosion
DNEL related information

General Population - Hazard via dermal route

Systemic effects

Long term exposure
Hazard assessment conclusion:
no hazard identified
Acute/short term exposure
Hazard assessment conclusion:
no hazard identified
DNEL related information

Local effects

Long term exposure
Hazard assessment conclusion:
medium hazard (no threshold derived)
Most sensitive endpoint:
skin irritation/corrosion
Acute/short term exposure
Hazard assessment conclusion:
medium hazard (no threshold derived)
Most sensitive endpoint:
skin irritation/corrosion

General Population - Hazard via oral route

Systemic effects

Long term exposure
Hazard assessment conclusion:
no hazard identified
Acute/short term exposure
Hazard assessment conclusion:
no hazard identified
DNEL related information

General Population - Hazard for the eyes

Local effects

Hazard assessment conclusion:
medium hazard (no threshold derived)

Additional information - General Population

Regarding acute and long-term local effects, local irritation on skin and/or mucous membranes, e. g. eye and respiratory tract as primary effect can be expected for fatty acids with a chain length ≤C12 due to the corrosive/irritation properties of the short- and mid-chain fatty acids C6 – C12, respectively.

Since no adequate dose descriptor for the corrosion/irritation effects are observed, no DNEL is calculated for local effects. However, appropriate risk management measures will be identified.

According to table E.3-1 in the “Guidance on information requirements and chemical safety assessment Part E: Risk Characterisation (ECHA, 2016), fatty acids, C8-18 (CAS# 90990-08-2) is allocated to the moderate hazard category based on classification as Skin Corr. 1C (H314) according to Regulation (EC) No 1272/2008.