Registration Dossier
Registration Dossier
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EC number: 204-445-3 | CAS number: 121-03-9
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Adequacy of study:
- other information
Data source
Reference
- Reference Type:
- publication
- Title:
- Uterotropic action in rats of Amsonic acid and three of its synthetic precursors
- Author:
- Smith, Emil R.
- Year:
- 1 992
- Bibliographic source:
- Journal of Toxicology and Envirnmental Health, 36:13-25
Materials and methods
- Type of study / information:
- Uterotropic Effects in Rats
Test guideline
- Qualifier:
- no guideline available
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 4-nitrotoluene-2-sulphonic acid
- EC Number:
- 204-445-3
- EC Name:
- 4-nitrotoluene-2-sulphonic acid
- Cas Number:
- 121-03-9
- Molecular formula:
- C7H7NO5S
- IUPAC Name:
- 2-methyl-5-nitrobenzenesulfonic acid
Constituent 1
Results and discussion
Any other information on results incl. tables
MNBSA in Saline
Treatment of female rats with single intraperitoneal doses of 1 -1000 mg/kg of MNBSA in saline was without adverse effects and did not alter either body weight or relative resulted in the death of one animal, but did increase relative uterine weight. Each of two additional animals died after doses of 10000 mg/kg.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
