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EC number: 204-528-4
CAS number: 122-20-3
According to Annex XI, Section 1.3 of REACH,
results obtained from valid qualitative or quantitative
relationship models ((Q)SARs) may indicate
the presence or absence of a certain dangerous property. Results of
(Q)SARs may be used instead of testing when the following conditions are
— results are derived from a (Q)SAR model
whose scientific validity has been established,
— the substance falls within the
applicability domain of the (Q)SAR model,
— results are adequate for the purpose of
classification and labelling and/or risk assessment, and
— adequate and reliable documentation of the
applied method is provided.
The long-term toxicity on aquatic
invertebrates has been assessed using the OECD QSAR Toolbox v4.4. A 21-d
NOEC for reproduction of Daphnia magna was derived using a trend
analysis of the standardized workflow for ecotoxicological endpoints as
provided by the Toolbox. The resulting 21-d NOEC was 27.5 mg/L. The
Substance is within the applicability domain of the model. A robust
study summary for this endpoint has been provided, which contains all
relevant and required information. Therefore, the Registrant will not
perform a study on the long-term toxicity to aquatic invertebrates.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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