Registration Dossier
Registration Dossier
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EC number: 241-004-4 | CAS number: 16940-66-2
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No long-term toxicity studies in aquatic invertebrates are available for sodium borohydride since it rapidly hydrolyzes in water to form sodium borate/boric acid and hydrogen gas with half-lives ranging from seconds to minutes at environmentally relevant pHs. Therefore, aquatic toxicity data for boric acid was used. .
Key value for chemical safety assessment
Additional information
No aquatic toxicity data is available for sodium borohydride since the compound rapidly hydrolyzes in water to form sodium borate/boric acid and hydrogen gas with half-lives ranging from seconds to minutes at environmentally relevant pHs.
Therefore, toxicity data for the toxicologically relevant hydrolysis product boric acid is applied for the safety assessment
The endpoints included in the dossier under environmental hazard assessment were reported from studies on the ecotoxicity of boron and various compounds, such as boric acid (H3BO3), anhydrous sodium tetraborate (Na2B4O7), and hydrated sodium tetraborates (Na2B4O7.xH2O). All endpoints were converted to concentrations of elemental boron (B) using the relative molar mass and then converted to NaBH4 for this IUCLID. Although a number of studies were available for exposure to invertebrates, the lowest reliable value was taken from a key study with zebrafish. The NOEC was 5.6 mg B/L which was converted to 17.5 mg NaBH4/L and used for freshwater PNEC derivation.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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