Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 912-664-7 | CAS number: -
Toxicity to other above-ground organisms
Administrative data
- Endpoint:
- toxicity to other above-ground organisms
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Study period:
- Not reported
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Non-guideline study with scientificallly defensible design, cobalt concentration not determined directly in feed.
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 976
- Report date:
- 1976
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Sixteen week dietary study with swine fed diet containing 4 dose levels of Co. 16 swine per treatment, growth assessed.
- GLP compliance:
- no
Test material
- Reference substance name:
- Cobalt dichloride
- EC Number:
- 231-589-4
- EC Name:
- Cobalt dichloride
- Cas Number:
- 7646-79-9
- Molecular formula:
- Cl2Co
- IUPAC Name:
- cobalt(2+) dichloride
- Details on test material:
- COCl2 6H2O
Constituent 1
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
not applicable
Sampling and analysis
- Analytical monitoring:
- no
Test substrate
- Vehicle:
- no
Test organisms
- Test organisms (species):
- other: swine
- Details on test organisms:
- 3 way cross Hampshire x Yorkshire x Duroc
Study design
- Study type:
- extended laboratory study
- Total exposure duration:
- 16 wk
Test conditions
- Test temperature:
- Not reported
- Humidity:
- Not reported
- Photoperiod and lighting:
- Not reported
- Reference substance (positive control):
- no
Results and discussion
Effect concentrations
- Duration:
- 16 wk
- Dose descriptor:
- NOEC
- Effect conc.:
- 200 mg/kg diet
- Nominal / measured:
- nominal
- Conc. based on:
- element
- Basis for effect:
- growth
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- A NOEC of 200 mg.kg diet resulted in no effect on swine growth after a minimum of 10 days of observation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
