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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
No data
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Meets generally accepted scientific standards with acceptable restrictions.

Data source

Reference
Reference Type:
publication
Title:
Occupational contact dermatitis from alkanolamine borates in metalworking fluids.
Author:
Bruze, M, Hradil, E, Erikson I-L, Gruvberger B and Widstrom
Year:
1995
Bibliographic source:
Contact Dermatitis 32: 24 - 27.

Materials and methods

Type of sensitisation studied:
skin
Study type:
other: Three patients; no other data.
Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Three patients were patch tested. Case No 1: Al-test, Astra Agency, Sweden with 25 µL of test agent. Case 2 & 3 ; Finn Chamber, Epicon OY, Finland with 15 µL of test agent.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Boric acid
EC Number:
233-139-2
EC Name:
Boric acid
Cas Number:
10043-35-3
Molecular formula:
H3BO3
IUPAC Name:
Boric acid
Details on test material:
- Name of test material: Boric acid tested at 3 % w/v.

Method

Type of population:
not specified
Controls:
No data
Route of administration:
dermal

Results and discussion

Results of examinations:
Not sensitising.

Applicant's summary and conclusion

Conclusions:
Boric acid tested at 3 % w/v in water showed no sensitisation in a patch test on three patients.