Registration Dossier
Registration Dossier
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EC number: 215-676-4 | CAS number: 1341-49-7
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No data are available for the substance, ammonium hydrogendifluoride (AMBI). The substance is water-soluble and, in aqueous environments, will dissociate to form hydrogen, fluoride and ammonium ions. Read-across data are available from the soluble fluoride salt, sodium fluoride and from ammonium chloride. Fluoride data give an arithmetic mean NOEC value of 8.9 mg/L. Data for non-ionised ammonia (NH3) give lower values but these are not considered relevant as AMBI will dissociate to form NH4 with little NH3 present.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 8.9 mg/L
Additional information
No data are available for the substance, ammonium hydrogendifluoride (AMBI). The substance is water-soluble and, in aqueous environments, will dissociate to form hydrogen, fluoride and ammonium ions. Read-across data are available from the soluble fluoride salt, sodium fluoride and from ammonium chloride.
Fluoride data
The EU RAR for HF summarises the effects of two reproductive studies of sodium fluoride on Daphnia magna. The two studies report NOEC values of 3.7 and 14.1 mg/L, with an arithmetic mean of 8.9 mg/L. The ICD reports additional EC50 values in the range of 10 - 48 mg/L.
Ammonia data
Rheinbold & Pescitelli (1990) investigated the long-term effects of ammonium chloride exposure to Daphnia magna. Survival was slightly less at the two highest test concentrations (73%) than at the other treatments (86-100%) but were not significantly different from the control. Daphnid growth (determined by length) was significantly reduced at the higher test concentration of 1.3 mg/L NH3-N. Mean length for the control and the high concentration were 3.52 and 3.02 mm respectively. Reproduction was also affected. The first young were produced on day 7 of the test in all treatments except the highest concentration, where no young were found until day 9. The average number of young/adult was significantly lower at that concentration-6.4 versus 24.6 in the control.
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