Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Hydrolysis

In accordance with column 2 of Annex VIII of the REACH regulation, testing for this endpoint is technically not feasible and does not need to be conducted since the test chemical is highly insoluble in water.

Biodegradation in water

Estimation Programs Interface Suite was run to predict the biodegradation potential of the test chemical in the presence of mixed populations of environmental microorganisms. The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called as Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that test chemical is expected to be not readily biodegradable.

Biodegradation in water and sediment

Estimation Programs Interface prediction model was run to predict the half-life in water and sediment for the test chemical. If released in to the environment, 1.26% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of test chemical in water is estimated to be 60 days (1440 hrs). The half-life (60 days estimated by EPI suite) indicates that the chemical is persistent in water and the exposure risk to aquatic animals is moderate to high whereas the half-life period of test chemical in sediment is estimated to be 541.66 days (13000 hrs). Based on this half-life value, it indicates that test chemical is persistent in sediment.

Biodegradation in soil

The half-life period of test chemical in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database. If released into the environment, 31.5% of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of test chemical in soil is estimated to be 120 days (2880 hrs). Based on this half-life value of test chemical, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low

Adsorption / desorption

The Soil Adsorption Coefficient i.e. Koc value of test chemical was estimated using EPI suite KOCWIN Program (v2.00) as 1491000000 L/kg (log Koc= 9.173) by means of MCI method at 25°C.  This log Koc value indicates that test chemical has very strong sorption to soil and therefore test chemical has negligible migration potential to ground water.

Additional information

Hydrolysis

In accordance with column 2 of Annex VIII of the REACH regulation, testing for this endpoint is technically not feasible and does not need to be conducted since the test chemical is highly insoluble in water.

Biodegradation in water

Predicted data for the test chemical and experimental studies for its read across substance were reviewed for the biodegradation end point and their results are summarized as below:

 

In the first study the Estimation Programs Interface Suite was run to predict the biodegradation potential of the test chemical in the presence of mixed populations of environmental microorganisms. The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called as Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that the chemical is expected to be not readily biodegradable.

 

In a supporting weight of evidence study from secondary sources, biodegradation study was conducted for assessing the effect of test chemical. The study was performed in accordance with the OECD TG 301 B at a temperature of 22 ± 2°C. Anaerobic bacteria collected from activated sludge of the sewage treatment plant was used as a test inoculum. Test chemical conc. used for the study was 10.7 mg/l and 20.2 mg/l, respectively. Aniline (20 mg/l) was used as a reference substance during the study. Reference substance aniline undergoes 84.3% degradation after 28 days. The percentage degradation of test chemical (at 10.7 and 20.2 mg/l conc.) was determined to be 6% and 5% by CO2 evolution parameter, respectively. Thus, based on percentage degradation, test chemical was considered to be not readily biodegradable.

 

For the test chemical, biodegradation study was conducted for assessing the effect of test chemical (J-CHECK, 2021). Activated sludge was used as a test inoculum. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. The percentage degradation of test chemical was determined to be 0% and 4% by oxygen consumption and HPLC parameter, respectively. Thus, based on percentage degradation, test chemical was considered to be not readily biodegradable.

 

On the basis of above results for test chemical, it is concluded that the test chemical is expected to be not readily biodegradable in nature.

Biodegradation in water and sediment

Estimation Programs Interface prediction model was run to predict the half-life in water and sediment for the test chemical. If released in to the environment, 1.26% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of test chemical in water is estimated to be 60 days (1440 hrs). The half-life (60 days estimated by EPI suite) indicates that the chemical is persistent in water and the exposure risk to aquatic animals is moderate to high whereas the half-life period of test chemical in sediment is estimated to be 541.66 days (13000 hrs). Based on this half-life value, it indicates that test chemical is persistent in sediment.

Biodegradation in soil

The half-life period of test chemical in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database. If released into the environment, 31.5% of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of test chemical in soil is estimated to be 120 days (2880 hrs). Based on this half-life value of test chemical, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low

Adsorption / desorption

The Soil Adsorption Coefficient i.e. Koc value of test chemical was estimated using EPI suite KOCWIN Program (v2.00) as 1491000000 L/kg (log Koc= 9.173) by means of MCI method at 25°C.  This log Koc value indicates that test chemical has very strong sorption to soil and therefore test chemical has negligible migration potential to ground water.