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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to terrestrial plants

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Administrative data

Link to relevant study record(s)

Description of key information

The effect of aspartic acid, N,N’-[methylenebis(2-methyl-4,1-cyclohexanediyl)]bis-, 1,1',4,4'-tetraethyl ester towards seedling emergence and seedling growth of terrestrial plants was tested according to the OECD Guideline No. 208 (ECT Oekotoxikologie GmbH, 2009b) yielding the following results:
NOEC (14 d): >= 100 mg a. s. /kg (Allium cepa, Avena sativa, Brassica napus)

Key value for chemical safety assessment

Short-term EC50 or LC50 for terrestrial plants:
100 mg/kg soil dw

Additional information

The test item had no adverse effects on seedling emergence and growth of higher plants at concentrations up to and including 100 mg a. s. /kg soil dry mass.

Study was performed with aspartic acid, N,N’-[methylenebis(2-methyl-4,1-cyclohexanediyl)]bis-, 1,1',4,4'-tetraethyl ester which is a structural analogue to aspartic acid, N,N’-(methylenedi-4,1-cyclohexanediyl)bis-, 1,1',4,4'-tetraethyl ester. Both substances are diethyl esters of aspartic acid linked to a dicyclohexylmethyldiamine moiety. The difference between these two substances is merely the presence of two methyl groups connected to the cyclohexane rings. This structural analogy was confirmed by theresponsible for the notification of both substances under the NONS regulation. Thedecided that test results obtained for one substance can be transferred to the other substance and that testing of both substances is usually not required. This decision is in accordance with the grouping of substances and read-across approach in Annex XI, 1.5 of the REACH Regulation.