Registration Dossier
Registration Dossier
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EC number: 203-299-8 | CAS number: 105-45-3
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The test item MAA was tested in a ready biodegradability and in an inherent biodegradability study. The ready biodegradation test was performed under GLP in 2009, according to OECD-guideline no. 301F (manometric respiration test). The inherent biodegradability was conducted in 1977 according to an early draft version for DIN 38 412 Part 25, before the later OECD-guideline for the Zahn-Wellens test was available. Test duration was 28 days for the ready biodegradation test and 5 days for the inherent biodegradability study. The ready biodegradability test was identified as key study with Klimisch 1, the inherent study was considered as supporting study with Klimisch 2, due to deviations from the current test guideline
- Ready biodegradability: 94% degradation after 28 days
- Inherent biodegradation: 100% degradation after 5 days
MAA was found to be readily and inherently biodegradable in both studies.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Key study - Ready biodegradability
The ready biodegradation test was performed under GLP in 2009, according to OECD-guideline no. 301F (manometric respiration test). Test duration was 28 days, biodegradation rate amounted to 94% within this time period. MAA was shown to be readily biodegradable.
Supporting study - Inherent biodegradability
The inherent biodegradability was conducted in 1977 according to an early draft version for DIN 38 412 Part 25, before the later OECD-guideline for the Zahn-Wellens test was available. Test duration was 5 days and the test item MAA showed an elimination rate of 100%. It can therefore be considered as inherently biodegradable.
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