Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
in vivo mammalian somatic cell study: cytogenicity / erythrocyte micronucleus
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Justification for type of information:
see attached justification
Cross-reference
Reason / purpose for cross-reference:
read-across: supporting information

Data source

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Potassium mercaptoacetate
EC Number:
252-038-4
EC Name:
Potassium mercaptoacetate
Cas Number:
34452-51-2
Molecular formula:
C2H4O2S.K
IUPAC Name:
potassium sulfanylacetate

Results and discussion

Test results
Key result
Sex:
male/female
Genotoxicity:
negative
Toxicity:
yes
Remarks:
clinical signs
Vehicle controls validity:
valid
Negative controls validity:
not examined
Positive controls validity:
valid

Applicant's summary and conclusion

Conclusions:
By analogy to NaTG, KTG is considered non-mutagenic in vivo.