Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 218-218-1 | CAS number: 2082-81-7
Endpoint summary
Administrative data
Description of key information
The ready biodegradation of 1,4-BDDMA was investigated in a study conducted according to OECD Guideline 310 (Headspace Test), over a period of 28 days and using predominantly domestic non-adapted activated sludge as inoculum. The biodegradation rate was determined by measurement of CO2 evolution.
The 10% level (beginning of biodegradation) was reached after 2 days. The pass level of 60% was reached after 9 days and the biodegradation came to 84 % after 28 days.
1,4-BDDMA was readily biodegradable fulfilling the 10-d window criterion.
Additional information
The ready biodegradation of 1,4-BDDMA was investigated in a study conducted according to OECD Guideline 310 (Headspace Test), adopted 23 March 2006, over a period of 28 days and using predominantly domestic non-adapted activated sludge as inoculum. The biodegradation rate was determined by measurement of CO2 evolution. Inoculum blank, toxicity control and procedural/functional control with the reference substance sodium benzoate were performed.The functional control reached the pass level pass level of 60% after 3 days.
The 10% level (beginning of biodegradation) was reached after 2 days. The pass level of 60% was reached after 9 days and the biodegradation came to 84 % after 28 days. The 95% confidence interval on day 28 was 76 - 92%
The biodegradation of the toxicity control reached 83% within 14 days and 89% after 28 days. The biodegradation of the reference item was not inhibited by the test itemin the toxicity control.The 95% confidence interval on day 28 was 86 - 93%
1,4-BDDMA was readily biodegradable fulfilling the 10-d window criterion.
In a supporting study the structural analogue 1,3-BDDMA has been tested for biodegradation:
The ready biodegradation of 1,3-BDDMA was investigated in a study conducted according to OECD Guideline 301 B (CO2 evolution test), adopted 17th July 1992, and EU Method C.4-C, 31 July 1992, over a period of 28 days and using domestic sewage as inoculum. The biodegradation rate was determined by measurement of CO2 evolution. Inoculum blank and procedural/functional control with the reference substance sodium acetate were performed.
The functional control reached the pass level >60% after 14 d (68.5%).
The 10-day window started on day 6. Biodegradation achieved 57% at the end of the 10 day window (day 16) and 74% at the end of the test period.
A degradation of 60% has to be reached in a 10-day window within 28 days in order to classify the test substance as readily biodegradable. Based on this criterion, 1,3-BDDMA is not readily biodegradable. But as the pass level is almost fulfilled (degradation slightly below 60%), the test substance can be considered as inherently biodegradable.
According to Annex IX 9.2.1.2. Column 2, a study on biodegradation in water and sediment does not need to be conducted as the substance is readily biodegradable (experimental result please see chapter 5.2.1).
According to Annex IX 9.2.1.3. Column 2, a study on biodegradation in soil does not need to be conducted as the substance is readily biodegradable (experimental result please see chapter 5.2.1.).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
