Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Dermal absorption

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Administrative data

Endpoint:
dermal absorption
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Justification for type of information:
Reference to CSR in section 13.1 for read-across justification
Cross-reference
Reason / purpose for cross-reference:
read-across source
Reference
Endpoint:
dermal absorption
Type of information:
other: Scientific review from a German authority determining maximum workplace concentrations with reference to original data
Adequacy of study:
weight of evidence
Study period:
1990
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Scientific review from a German authority determining maximum workplace concentrations with reference to original data; info on absorption of 1-pentyl acetate through skin; conclusions based on calculation and no official test guideline
Principles of method if other than guideline:
estimation of dermal absorption

Data source

Materials and methods

Principles of method if other than guideline:
estimation of dermal absorption

Test material

Constituent 1
Chemical structure
Reference substance name:
Isopentyl acetate
EC Number:
204-662-3
EC Name:
Isopentyl acetate
Cas Number:
123-92-2
Molecular formula:
C7H14O2
IUPAC Name:
3-methylbutan-1-ol

Results and discussion

Applicant's summary and conclusion