Registration Dossier
Registration Dossier
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EC number: 203-809-9 | CAS number: 110-86-1
Toxicity to terrestrial arthropods
Administrative data
Link to relevant study record(s)
Description of key information
Waiver: toxicity testing on terrestrial arthropods is not required, since direct and indirect exposure of the soil compartment is unlikely.
Key value for chemical safety assessment
Additional information
According to Regulation (EC) No.1907/2006, Annex IX, Section 9.4, Column 2, and Annex X, Section 9.4, Column 2, studies on effects on terrestrial organisms (including terrestrial arthropods) do not need to be conducted if direct and indirect exposure of the soil compartment is unlikely; long-term toxicity testing may be considered for those substances that have a high potential to adsorb to soil or which are very persistent. Pyridine has a low potential for adsorption to soil/sediment (Kow = 4.365, log Kow =0.64), and is not classified as very persistent. The chemical safety assessment for this substance demonstrates that 1) the exposure levels estimated in all relevant scenarios do not exceed the appropriate PNEC; and 2) the likelihood and severity of an event occurring due to the physicochemical properties of the substance is negligible, according to Annex 1, Section 6.4. Therefore, the criteria for adaptation are met. Specifically, all risk characterization ratios are under 1.0, and direct and indirect exposure to soil is unlikely as demonstrated by the attached exposure assessments. Therefore, toxicity testing on terrestrial arthropods is not indicated.
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