Registration Dossier
Registration Dossier
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EC number: 213-834-7 | CAS number: 1025-15-6
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: Documentation is insufficient for assessement
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- publication
- Title:
- K woproci o tokcischnosti cianurowoi kislotui i trioallilisozianurata
- Author:
- Bidnenko, L.I.
- Year:
- 1 969
- Bibliographic source:
- Gig. Primen. Polim. Mater., Izdelii, Jz Nikh, 299-302
Materials and methods
- Principles of method if other than guideline:
- The test item was applied to the intact dorsal shaved skin of rats for 2 hours.
- GLP compliance:
- no
- Test type:
- standard acute method
- Limit test:
- no
Test material
- Reference substance name:
- 1,3,5-triallyl-1,3,5-triazine-2,4,6(1H,3H,5H)-trione
- EC Number:
- 213-834-7
- EC Name:
- 1,3,5-triallyl-1,3,5-triazine-2,4,6(1H,3H,5H)-trione
- Cas Number:
- 1025-15-6
- Molecular formula:
- C12H15N3O3
- IUPAC Name:
- tris(prop-2-en-1-yl)-1,3,5-triazinane-2,4,6-trione
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- TEST ANIMALS
- Weight at study initiation: 100 - 120 g
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- unchanged (no vehicle)
- Details on dermal exposure:
- TEST SITE
- Area of exposure: back (3x3 cm) - Duration of exposure:
- 2 hours
- Doses:
- no data
- No. of animals per sex per dose:
- 6 animals per dose
- Control animals:
- not specified
Results and discussion
Effect levelsopen allclose all
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- ca. 2 750 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: calculated according to the method by Behrens and Schlosser
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- ca. 2 480 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: calculated according to the method by Prosorowskj
Any other information on results incl. tables
The test substance is easily soaked into the skin and caused general toxic effects including death of animals. No skin irritation was observed.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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