Registration Dossier
Registration Dossier
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EC number: 203-765-0 | CAS number: 110-41-8
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2010-07-30
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7570 (Partition Coefficient, n-octanol / H2O, Estimation by Liquid Chromatography)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- - Names of test material (as cited in study report): Aldehyde C12 MNA Pure, 2-methylundecanal
- Substance type: Colourless liquid
- Physical state: Liquid
- Impurities (identity and concentrations): No data
- Composition of test material, percentage of components: No data
- Isomers composition: No data
- Purity test date: No data
- Lot No: VE00104771
- Expiration date of the lot: No data
- Stability under test conditions: No data
- Storage condition of test material: No data - Analytical method:
- high-performance liquid chromatography
- Type:
- log Pow
- Partition coefficient:
- 4.9
- Temp.:
- 35 °C
- Remarks on result:
- other: pH not determined
- Details on results:
- HPLC PROCEDURE
- Representative chromatograms are presented in Appendices 3 and 4 (attached). - Conclusions:
- The n-octanol/water partition coefficient (Log Pow) was determined to be 4.9
Reference
Description of key information
Partition coefficient, Log Pow = 4.9 (OECD 117)
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 4.9
- at the temperature of:
- 35 °C
Additional information
In Givaudan study No. 10-E160, to OECD 117 and GLP, the partition coefficient was determined to be as follows; Log Pow was 4.9 at a temperature of 35 °C.
The determination was performed at 35°C (temperature of the column), but the value obtained can be considered to represent the value at an unspecified, probably ambient temperature since no mention is made in the guidelines of the temperature at which the tabulated reference substances log Pow values were determined. Partition coefficients of the test and reference substances are assumed to vary with temperature in the same way.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
