Registration Dossier
Registration Dossier
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EC number: 203-852-3 | CAS number: 111-27-3
Toxicity to birds
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
Short-term toxicity
Only short term oral toxicity data to birds exists. A 21 day LC50 value of 176000 ppm has been determined for the effects of dodecanol on mortality of Gallus gallus domesticus (chicken). The study reflects the only value available with this substance for this endpoint.
However this study has not been selected as key since ECHA (2011, Guidance on information requirements and chemical safety assessment Part B: Hazard Assessment Dec 2011, version 2.1) reads: "due to poor correlation between short and long term effects, only long term studies are considered suitable for CSA purposes".
Long-term toxicity
In accordance with Column 2 of REACH Annex X, studies on long-term or reproductive toxicity to birds (required in section 9.6.1) do not need to be conducted due to the existence of mammalian data demonstrating no long term systemic effects to higher organisms. Secondary poisoning assessment is not required for this substance due to its expected low bioconcentration factor and lack of systemic effects in mammals. In addition, bioaccumulation is not of concern for this substance (Log Kow <3).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
