Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-980-7 | CAS number: 101-83-7
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
LC50 (48 hours) for freshwater fish (Danio rerio): 62 mg/L (EU Method C.1 Acute toxicity for fish, static test)
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 62 mg/L
Additional information
For fish (Danio rerio) a 96 h-LC50 of 62 mg/L was obtained. The GLP study was conducted in a static test according to Directive/ECC (67/548/EEC), Annex V, C.1 “Acute toxicity to fish”, comparable to OECD TG 203 (Bayer AG, 1992a). The stability of the test substance was experimentally determined with GC during the exposure period. The results are related to measured concentrations, although the recovery rates were > 96 %.
Another GLP study, using the same TG, reported a 96 h-LC50 of 12 mg/L (measured) for Oryzias latipes in a semi-static test (EA Japan, 1999a). Although pH was significantly increased (pH 9.0-9.8) with increasing dicyclohexylamine concentration during incubations at concentrations ≥18 mg/L, no pH control assay and no tests with neutralized dicyclohexylamine were performed. Since mortality occurred exclusively within 24 h of incubation and remained unchanged during the time course of the incubations, it cannot be excluded that the elevated pH contributed to mortality (EA Japan, 1999a).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
