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Physical & Chemical properties

Viscosity

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Reference
Endpoint:
viscosity
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Test was conducted to Method 114 of the OECD Guidelines for Testing of Chemicals and under GLP.
Qualifier:
according to guideline
Guideline:
OECD Test Guideline 114 (Viscosity of Liquids)
GLP compliance:
yes (incl. QA statement)
Type of method:
rotational viscometer (dynamic)
Key result
Temp.:
20°C
Parameter:
dynamic viscosity (in mPa s)
Value:
2 137
Key result
Temp.:
40°C
Parameter:
dynamic viscosity (in mPa s)
Value:
537.4

The viscometer rotational speed, sheer rate, sheer stress, viscosity, actual sample temperature and percentage torque for each determination are shown in the following tables:

Table 3.2 – 20.0 ± 0.5 °C

Rotational Speed (rpm)

Shear Rate (sec-1)

Shear Stress (N/m2)

Viscosity (mPa.s)

Temperature (°C)

Torque (%)

12

4.08

8.73

2.140 x 10^3

20.0

85.6

12

4.08

8.71

2.135 x 10^3

20.0

85.4

12

4.08

8.72

2.137 x 10^3

20.0

85.5

Mean Viscosity = 2.137 x 10^3 mPa.s

Table 3.3 – 40.0 ± 0.5 °C

Rotational Speed (rpm)

Shear Rate (sec-1)

Shear Stress (N/m2)

Viscosity (mPa.s)

Temperature (°C)

Torque (%)

12

4.08

2.19

5.374 x 10^2

40.1

21.5

12

4.08

2.19

5.374 x 10^2

40.1

21.5

12

4.08

2.19

5.374 x 10^2

40.1

21.5

Mean Viscosity = 5.374 x 10^2 mPa.s

3.1.3 Conclusion

The viscosity of the test item has been determined at 20.0 ± 0.5 °C and 40.0 ± 0.5 °C, the results are shown in the following table:

Table 3.4

Temperature (°C)

Viscosity (mPa.s)

20.0 ± 0.5 °C

2.137 x 10^3

40.0 ± 0.5 °C

5.374 x 10^2

Conclusions:
The rotational viscometer method compatible with Method 114 of the OECD Guidelines for Testing of Chemicals was used to study the viscosity of the test substance PR-4758, and the vicosity was measured as 2.137 x 10^3 mPa.s at 20 deg C and 5.374 x 10^2 mPa.s at 40 deg C.
Executive summary:

The rotational viscometer method compatible with Method 114 of the OECD Guidelines for Testing of Chemicals was conducted under GLP to study the viscosity of the test substance PR-4758, and the vicosity was measured as 2.137 x 10^3 mPa.s at 20 deg C and 5.374 x 10^2 mPa.s at 40 deg C

Description of key information

Viscosity = 2.137 * 10^3 and 5.374 * 10^2 mPa.s at 20 and 40 °C, respectively; OECD guideline 114 (1981); Jein, 2013

Key value for chemical safety assessment

Viscosity:
2 137 mPa · s (dynamic)
at the temperature of:
20 °C

Additional information

One key study is available which derived viscosity of PR-4758. The study was conducted in accordance with OECD guideline 114 to GLP standards at a GLP certified laboratory.