Registration Dossier
Registration Dossier
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EC number: 207-330-6 | CAS number: 462-95-3
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Lab not following OECD guidelines or GLP
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 987
- Report date:
- 1987
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Internal SOP: TA 310, TA 160, TA 120
- Deviations:
- not specified
- Principles of method if other than guideline:
- 20 ml/kg administrated as received/ Method of calculation: Weil method
- GLP compliance:
- no
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- Diethoxymethane
- EC Number:
- 207-330-6
- EC Name:
- Diethoxymethane
- Cas Number:
- 462-95-3
- Molecular formula:
- C5H12O2
- IUPAC Name:
- diethoxymethane
Constituent 1
Test animals
- Species:
- rat
- Strain:
- other: CRL: CD (SD) BR
- Sex:
- male/female
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- unchanged (no vehicle)
- Doses:
- 20 ml/kg
- No. of animals per sex per dose:
- 5
- Control animals:
- no
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 20 mL/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: 95% CL: no range calculable
- Mortality:
- none
- Clinical signs:
- other: all normal
Any other information on results incl. tables
Skin absorption: Not evident
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Not toxic by dermal route
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