Registration Dossier
Registration Dossier
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EC number: 234-204-8 | CAS number: 10595-49-0
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Clarke (2012) reports a 3-hr EC50 for toxicity to microorganisms of 80 mg/L and a 3-hr NOEC of 32 mg/L.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 80 mg/L
- EC10 or NOEC for microorganisms:
- 32 mg/L
Additional information
A reliable toxicity study with microorganisms is available for KEL3587 and is included in this dossier.
Clarke (2012) conducted a reliable (Klimisch 1) GLP compliant study following OECD 209 methods withKEL3587. A mixed population of activated sewage sludge micro-organisms was obtained from a sewage treatment plant. Organisms were exposed concentrations of 18, 32, 56, 100 and 180 mg/L in a static test for 3 hours. The effect of the test item on the respiration of activated sewage sludge micro-organisms gave a 3-Hour EC50 value of 80 mg/L, 95% confidence limits 72 - 89 mg/L, based on oxygen consumption. The NOEC after 3 hours exposure was 32 mg/L.
A reliable toxicity study with microorganisms is available for KEL3587 and is included in this dossier. Clarke (2012) reports a 3-hr EC50 for toxicity to microorganisms of 80 mg/L and a 3-hr NOEC of 32 mg/L. Consequently these values will be taken as the toxicity in microorganisms endpoint for KEL3587.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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