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Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Description of key information

 Liedtke (2010) reports a 72-hr LC50 for toxicity in Pseudokirchneriella subcapitata of 0.097 mg/L and a 72-hr NOEC of 0.016 mg/L, based on growth.

Key value for chemical safety assessment

EC50 for freshwater algae:
0.097 mg/L
EC10 or NOEC for freshwater algae:
0.016 mg/L

Additional information

A reliable toxicity study with algae is not available for KEL3587. However, a reliable (Klimisch 1) toxicity study with algae has been conducted on the analogue, KEU4587 and is included in this dossier.

 

Liedtke (2010) conducted a reliable (Klimisch 1) GLP compliant study following OECD 201 methods with the analogue, KEU4587. The algae,Pseudokirchneriella subcapitata, were exposed to the test substance at nominal concentrations of 0.054, 0.116, 0.25, 0.54, 1.16 and 2.5 mg/L and measured concentrations of 0.016, 0.032, 0.077, and 0.351 mg dry matter / L for 72 hrs under static conditions. The lowest two test concentrations were not confirmed analytically. The 72-h EC50 was 0.097 mg/L, based on growth. The 72-hr NOEC was 0.016 mg/L, based on growth.  

               

A reliable toxicity study with algae is not available for KEL3587. However, a reliable (Klimisch 1) toxicity study with algae has been conducted the analogue, KEU4587 and is included in this dossier. Liedtke (2010) reports a 72-hr LC50 for toxicity in Pseudokirchneriella subcapitata of 0.097 mg/L and a 72-hr NOEC of 0.016 mg/L, based on growth. Consequently these values will be taken as the toxicity in algae endpoint for KEL3587.