Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-874-3 | CAS number: 111-48-8
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
Data source
Reference
- Reference Type:
- publication
- Title:
- IPCS, International Programme on Chemical Safety, Poisons Information Monograph 980, Thiodiglycol
- Author:
- WHO
- Year:
- 2 001
- Bibliographic source:
- [http://www.inchem.org/documents/pims/chemical/pim980.htm]
Materials and methods
- Type of study / information:
- Type of experience: Human
Test material
- Reference substance name:
- Ethane-1,2-diol
- EC Number:
- 203-473-3
- EC Name:
- Ethane-1,2-diol
- Cas Number:
- 107-21-1
- Molecular formula:
- C2H6O2
- IUPAC Name:
- ethylene glycol
Constituent 1
Results and discussion
- Results:
- Based on the structural similarity to ethylene glycol, thiodiglycol may produce depression of the central nervous system, metabolic acidosis and renal failure in severe intoxication.
Applicant's summary and conclusion
- Conclusions:
- Thiodiglycol may produce depression of the central nervous system, metabolic acidosis and renal failure in severe intoxication.
- Executive summary:
Based on the structural similarity to ethylene glycol, thiodiglycol may produce depression of the central nervous system, metabolic acidosis and renal failure in severe intoxication.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
