Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 253-775-4 | CAS number: 38083-17-9
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
The substance is considered as not bioaccumulative. It is proposed to use a BCF of 156.3 L/kg in the chemical safety assessment as this was the maximum predicted BCF.
Key value for chemical safety assessment
- BCF (aquatic species):
- 156 L/kg ww
Additional information
For the test substance, a log Kow of 3.83 (see section 4.7 of the IUCLID dataset) was determined experimentally. Therewith the log Kow is below the trigger value of 4 (GHS) for bioaccumulation. It is generally assumed that non-ionised organic substances with a log Kow below 4 (GHS) are not significantly bioaccumulative (R.7.10.5). Furthermore, the measured log Kow of 3.83 is clearly below the B screening criterion of log Kow ≤ 4.5 for the PBT discussion.
To support this result, the bioaccumulation factor (BCF) for fish was calculated using a QSAR based software approach. The QSAR model used by Episuite (Epiweb 4.1, BCFBAF program v3.01) is based on correlations between BCF and chemical hydrophobicity (as modelled by log Kow). Episuite BCFBAF calculated a BCF value of 156 L/kg body weight (based on log Kow 3.83). This value is below the cut-off value of 2000 L/kg triggering classification of substances as bioaccumulative.
Hence, based on these results, it is concluded that the B criterion is not met and the substance is not considered as bioaccumulative.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
