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EC number: 266-564-7
CAS number: 67075-37-0
The test substance is with high probability acutely not harmful to aquatic organisms.
The test substance is with high probability acutely not harmful to
The inhibition of the degradation activity of activated sludge is not
anticipated when introduced in appropriate low concentrations.
The test substance belongs to the category of perylene pigments as
indicated by its chemical core structure. Based on this structure and
the chemical and biological stability of perylene pigments under
environmental conditions, data from structural analogue perylenes can be
used to cover this endpoint required under REACh if no data for the
original test substance is available.
The acute toxicity to fish was examined in a GLP guideline study
according to JIS K 0102-1974 item 55 with the test species Oryzias
latipes [BASF AG 1989]. The test substance was tested as dispersion
(10.5% dye, 20% Cremophor RH 40, 70% bidistilled water). At test
termination after 96 h, a LC50 of > 1050 mg/L based on nominal
concentration of dye was determined.
A study on the toxicity of the analogue substance CAS 81-33-4 to Daphnia
magna has been conducted according to OECD guideline 202 following a
static test system setup [BASF SE, 2012]. At test termination after 48 h
no toxicity was observed up to the limit of solubility of the test
substance (EC50 > 0.0065 mg/L; measured).
The acute toxicity of the test substance to aquatic invertebrates
has been examined in a GLP guideline study according to EEC Directive
92/32/EEC. The test animals of the species Daphnia magna were exposed to
the test substance for 48 h in a static test system set up. At test
termination an EC50 > 100 mg/l was determined [BASF AG, 1998]. Similar
results were obtained for Perylen Schwarz/Black I (EC 479-300-2) and
Perylen Schwarz/Black II (EC 475-310-6) were toxicity to Daphnia magna
was examined in 48 hour static limit tests according to OECD guideline
202, respectively. At test termination an EC50 of > 100 mg/l based on
nominal test substance concentrations was determined, respectively (BASF
AG 2005, 2006).
The toxicity of the analogue substance CAS 4948-15-6 on aquatic algae
was investigated in a GLP guideline study according to OECD 201 with Pseudokirchneriella
subcapitata [BASF SE, 2012]. The substance had no observable
inhibitory effect on algae growth up to its saturation limit in the test
media and under test conditions. The EC50 value (based on growth rate
after 72 h of exposure) was determined to be > 100 mg/L (nominal). The
inhibiting abilities of Perylen Schwarz/Black I (EC 479-300-2) and
Perylen Schwarz/Black II (EC 475-310-6) to Pseudokirchnerella
subcapitata were examined in GLP studies according to OECD guideline
201, respectively. After 72 h the EC50 value for Perylen Schwarz/Black I
and Perylen Schwarz/Black II was determined to be > 100 mg/L based on
the nominal concentration of the test substances (BASF AG 2006). No
effect was observed up to the solubility limit of the test substance in
The acute toxicity of the analogue substance CAS 81-33-4 to aquatic
plants has been examined in a GLP guideline study according to OECD 221
with the test species Lemna gibba [BASF SE, 2012]. At test
termination after 7 d, an ECr50 > 0.007 mg/L (measured) relating to
growth rate (frond rate and dry weight, respectively) was determined.
The changes in the respiration rate of activated sludge in presence of
the analogue perylenes (CAS 4948-15-6, CAS 81-33-4, CAS 128-69-8) were
investigated in three guideline studies according to OECD 209 and ISO
8192, respectively, with activated sludge as inoculum. At test
termination after 30 minutes effect concentrations > 700 mg/L (nominal)
were determined [BASF AG 1998; BASF AG 1999; BASF AG 1986]. Additionally,
several oxygen consumption tests which were conducted according to ROBRA
(DIN 38412, part 27) are available for the toxicity assessment. The
bacteria Pseudomonas putida was exposed to different test concentrations
of the following analogue substances: CAS 3049-71-6, CAS 5521-31-3 and
CAS 128-69-8 [BASF AG 1991; BASF AG 1990; BASF AG 1986]. After an
exposure period of 30 minutes the lowest determined effect concentration
was 1250 mg/L (nominal).
All tests were run with concentrations above the water solubility of the
test substance and its analogues, respectively. Thus, no effects in the
range of the water solubility of the substance were determined.
The hazard assessment of the substance reveals neither a need to
classify the substance as dangerous to the environment, nor is it a PBT
or vPvB substance, nor are there any further indications that the
substance may be hazardous to the environment. Therefore, and for
reasons of animal welfare long-term toxicity testing in fish and aquatic
invertebrates is not provided.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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