Pentan-2-one

Density

Link to relevant study record(s)

Reference

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

May 2013

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Deviations:

no

GLP compliance:

no

Type of method:

oscillating densitimeter

Type:

relative density

Density:

0.806 g/cm³

Temp.:

20 °C

*INFORMATION REQUIREMENTS-The Study does not need to be conducted if: the substance is only stable in solution in a particular solvent and the solution density is similar to that of the solvent. In such cases, an indication of whether the solution density is higher or lower than the solvent density is sufficient; or the substance is gaseous at room temperature. In this case, an estimation based on calculation shall be made from its molecular weight and the Ideal Gas Laws. Summary should include the numerical value and temperature at which it was measured, purity of the sample used, physical state, method used and reference substance.

 

 

 

METHOD

 

The density at 20 ⁰C of MPK was measured using a Mettler DE40 oscillating tube densitometer. Testing was conducted using Method A3 of Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC).  The test method conforms to ASTM D4052-09. Density was converted to the relative density compared to water at 4 ⁰C. 

 

PROCEDURE

 

The instrument was first qualified by measuring the density of the Cannon standard reference oil N4 at 20 ⁰C. The measured density was 0.7913 g/mL versus the standard reference value of 0.7913 g/mL.

 

 After running the standard reference material, the cell was cleaned and dried and approximately 3 ml of liquid isobutyric anhydride was injected into the sample analysis tube. When the sample equilibrated to the set temperature, an audible signal indicated that the density value could be read from the instrument. The measurement was repeated with a fresh sample.

 

RESULTS/CONCLUSION

 

The density at 20 ⁰C was determined to be 0.8058 +/- 0.0001 g/ml, which converts to a relative density of 0.8058 +/- 0.0001. The results of the two measurements are reported below in Table 1.

 

Table VI-1. Results of density measurements at 20 ⁰C

 

   Run         Density, g/ml

1                     

2                     

Conclusions:

The density at 20 ⁰C was determined to be 0.8058 +/- 0.0001 g/ml, which converts to a relative density of 0.8058 +/- 0.0001.

Executive summary:

The density at 20 ⁰C was determined to be 0.8058 +/- 0.0001 g/ml, which converts to a relative density of 0.8058 +/- 0.0001.

Description of key information

The density at 20 ⁰C was determined to be 0.8058 +/- 0.0001 g/ml, which converts to a relative density of 0.8058 +/- 0.0001. 

Key value for chemical safety assessment

Relative density at 20C:

0.806