2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

1989

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

yes

Remarks:

- It was used in the lowest vapour pressure range the thermobalance method instead of the gas saturation method.

GLP compliance:

no

Type of method:

effusion method: vapour pressure balance

Remarks:

thermogravimetry analysis

Temp.:

25 °C

Vapour pressure:

<= 0 Pa

Remarks on result:

other: extrapolated

Transition / decomposition:

yes

Remarks:

melting point

Transition temp.:

114.8 °C

Vapour pressure at 10°C above transition temperature:

0.21 Pa

Vapour pressure at 20°C above transition temperature:

0.44 Pa

Transition / decomposition:

yes

Remarks:

decomposition

Transition temp.:

> 275 °C

Temperature (°C)	Vapour pressure extrapolated (Pa)
25	≤ 6.0x10^-7
20	≤ 2.5x10^-7
94.8	≤ 1.1x10^-2
104.8	≤ 3.4x10^-2
114.8	≤ 9.8x10^-2
124.8	≤ 2.1x10^-1
134.8	≤ 4.4x10^-1

T'_A (11 Pa): 185 °C (measured)

ΔH_V (heat of evaporation): ≥ 99.4 kJ/mol

ΔH_F (heat of fusion): 29.1 kJ/mol (DSC)

ΔH_S (heat of sublimation): ≥ 128.9 kJ/mol

F_P (melting point): 114.8 °C (DSC)

* Evaluation of vapour pressure using 2nd scan only.

Only upper limits of vapour pressure could be given in this report, because of decomposition of the sample during the thermal treatment.

Thermogravimetric analysis:

Temperature in°C	Weight loss in % weight
25 - 200	<0.1
225	0.2
250	1.6
275	6.6
300	24.8
325	70.0
350	96.8
375	98.4
400	99.2

Experimental conditions:

Intrument: Thermobalance Perkin-Elmer TGS-1

Sample pan: Aluminium; Sample weight:1.64 mg; Atmosphere: N2 (high purified = 99.999 %) gas flow 30 cm³/min; Heating rate: 20 °C/min;

Temperature calibration: Magnetic standards: Alumel and Nickel

Conclusions:

The vapour pressure of test substance was extrapolated to be ≤0.0000006 Pa at 25°C

Executive summary:

In this guideline (OECD 104) study the vapour pressure of the test material (EC 404-360-3) was determined to be ≤0.0000006 Pa at 25°C

Description of key information

Study conducted to recognised testing guideline.

Key value for chemical safety assessment

Vapour pressure:

0 Pa

at the temperature of:

25 °C

Additional information

The vapour pressure was determined by Thermogravimetry (Diffusion controlled evaporation)

≤0.0000006 Pa at 25°C  (extrapolated)