Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report Date:
2013

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Principles of method if other than guideline:
0.2g of V171629/FQ is weighed into three glass vessels. 50ml of water is added to each vessel. The vessels are tightly stoppered and then stirred at 30 °C. After one day, one of the vessels is equilibrated for 24 hours at the test temperature with occasional shaking. The contents of the vessel are then centrifuged at the test temperature and the concentration of the test substance in the clear aqueous phase is determined by HPLC.
The other two flasks are treated similarly after initial equilibration at 30 °C for two and three days respectively.
GLP compliance:
no
Type of method:
other: HPLC method

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Water solubility
Water solubility:
ca. 0.46 g/L
Temp.:
30 °C
Remarks on result:
other: The concentrations measured after two and three days do not differ more than 15% .

Applicant's summary and conclusion

Conclusions:
moderately soluble (100-1000 mg/L)